Discussing the famous article in The LANCET Vol 49 August 2024 Overall cardiovascular mortality is expected to increase by 91.2% between 2025 and 2050, despite a 23.0% decline in the age-standardized cardiovascular mortality rate (ASMR). Coronary heart disease (115 deaths per 100,000 population) and stroke (63 deaths per 100,000 population) will re…

Drugs are an important cause of liver injury. More than 900 drugs, toxins, and herbs have been reported to cause liver injury, and drugs are responsible for 20–40% of all cases of fulminant liver failure. Approximately 75% of idiosyncratic drug reactions result in liver transplantation or death. Drug-induced liver injury is the most common reason f…

The World Health Organization (WHO) defines pharmacovigilance as the science and activities concerned with the detection, assessment, understanding and prevention of adverse effects or any other problems associated with medicines. According to this general definition, the main objectives of applicable pharmacovigilance legislation are: to prevent h…